Thrombophlebitis migrans including Mondors syndrome and autoimmune hemolytic anemia in ulcerative colitis ; case report and review of the literature

Thromboembolic events occur in UC and Crohn’s disease. Activation of clotting factors and thrombocytosis are common. In ulcerative colitis, increased levels of factor V, factor VIII and fibrinogen and decreased levels of antithrombin III have been demonstrated. Deep vein thrombosis and pulmonary emboli affect patients with severe disease and may occur after colectomy. Thromboembolic events in the eye or intracranial vessels have been described. Coombs positive hemolytic anemia has occasionally been reported in patients with ulcerative colitis. In some of these rare cases, hemolytic anemia was the main problem of the patient and was cured by colectomy.